Scientific Studies and Certifications

DermaSilk is the innovative line of therapeutic clothing conceived by Alpretec for people who suffer from problems or skin diseases. Its efficacy derives from the combination of the beneficent properties of pure silk fibroin, enhanced by the knitting process, with permanent antimicrobial activity.

Its efficacy in different types of skin diseases is certified by numerous clinical studies and laboratory tests.

Clinical studies:

ATOPIC DERMATITIS/ECZEMA:

DermaSilk in long-term control of infantile atopic dermatitis: a double blind randomized controlled trial (Fontanini C., Berti I., Monasta L., Longo G. Published on Giornale Italiano di Dermatologia e Venereologia, vol.148, No 3, 2013)

Evaluation of the efficacy of medicated silk in the treatment of Atopic Dermatitis in children and adults (F. Piccirillo, S. Bondino, A. Trink, V.C. Battarra, G. Stinco. Dermatological Clinic - Department of Pathology and Experimental Medicine - University of Udine; UOSD Oncologic Dermatology, Hospital of S.Anna e S. Sebastiano Caserta). Poster presented at the 48th ADOI Congress, Venice, 4.7 November 2009).

A Randomized Double-Blind study to investigate the clinical efficacy of adding a non-migrating antimicrobial to a Special Silk Fabric in the Treatment of Atopic Dermatitis (G. Stinco, F. Piccirillo, F. Valent – Dermatology 2008; 217:191-195);

Action of a silk fabric with antimicrobial in children with atopic dermatitis: a 3-month clinical experiment (Koller DY et al., Department of Paediatrics, Vienna University Hospital, Austria. - Published in Pediatric Allergy Immunology, 2007; 18: 335-338);

Antimicrobial Silk Clothing in the Treatment of Atopic Dermatitis Proves Comparable to Topical Corticosteroid Treatment (Senti G. et al., Zurich University Hospital, Switzerland - Published in Dermatology, 2006; 213: 228-233);

Clinical effectiveness of a silk fabric in the treatment of atopic dermatitis (G. Ricci et al., Bologna University Hospital, Italy - Published in the British Journal of Dermatology, 2004; 150: 127-131);

 

VULVAR DISEASES:

- Effectiveness of silk fabric underwear as an adjuvant tool in the management of vulvar lichen simplex chronicus: results of a double-blind randomized controlled trial, Corazza M, Borghi A, Minghetti S, Toni G, Virgili A et al. Menopause 2015; Vol. 22, No. 8.

- DermaSilk® briefs in recurrent vulvovaginal candidosis. An alternative option in long-lasting disease, D’Antuono A, Bellavista S, Gaspari V et al. Minerva Ginecol 2013; 65:697-705.

Use of DermaSilk briefs in recurrent vulvovaginal candidosis: safety and effectiveness (D’Antuono A., Baldi E., Bellavista S., Banzola N., Zauli S., Patrizi A.). MYCOSES, VOLUME 55, ISSUE 3 (e85-e89), may 2012.

- DermaSilk® Briefs in Vulvar Lichen Sclerosus: An Adjuvant Tool (D'Antuono et al., Department of Internal Medicine, Geriatry and Nephrology -Section of Dermatology - University of Bologna; published on Journal of Lower Genital Tract Disease 2011; Volume 15, Number 4: 287-291. American Society for Colposcopy and Cervical Pathology).

- "Clinical effectiveness of a special silk textile in the treatment of recurrent pediatric inflammatory vulvistis: an open label pilot study"
A. Patrizi, F. Giacomini, C. Gurioli, I. Neri. Pubblicato su Giornale Italiano di Dermatologia e Venereologia 2011; Volume 146: 317-320.

- Alternative therapy of recurrent vulvar diseases -P. Betto, A. Barba (Verona), A. Belloni Fortina (Padua), M. Bertazzoni (Vicenza), A. Cantù (Milan), M. De Carli (Treviso), A. Di Ladro (Bergamo), L. Germi (Vicenza), C. Rigoni (Milan), D. Schena (Verona), R. Strumia (Ferrara) – edited by Donne Dermatologhe Italia; Poster presented at the 81st SIDeMaST National Congress; Turin 31 May-3 June 2006


SKIN REACTIONS TO RADIOTHERAPY AND CHEMOTHERAPY:


- Skin reactions to radioterapy;
“Evaluation of medicated silk for topical use in acute local reactions in cancer patients. Poster presentation XXIII Congress of  Associazione Italiana Radioterapia Oncologica, Giardini Naxos-Taormina 2013

- Skin reactions to chemotherapy.
“Antimicrobial silk clothing as an adjuvant tool in the treatment of chemotherapy - induced skin reactions.” Poster presentation 22° Congress of the European Academy of Dermatology and Venereology, Istanbul 2013

ACNE VULGARIS:

- “Silk textile with antimicrobial AEM5772/5 (Dermasilk): a pilot study with positive influence on acne vulgaris on the back”  Schaunig C, Kopera D. - International Journal of Dermatology 2017."

Tests:
- Chemical Test: Certifies that the polymerised antimicrobial on DermaSilk silk knitwear does not leech into the environment, even after washing, and does not transfer any substance onto the skin. (Test carried out by Prof. P. Mandrioli of the CNR – Istituto ISAC – Bologna);
- Microbiological Test: Certifies that the polymerised antimicrobial on DermaSilk silk knitwear does not alter the natural bacterial flora of the skin. (Test carried out by Prof. P. Mandrioli of the CNR – Istituto ISAC – Bologna);
- Microbiological Test: Certifies that the polymerised antimicrobial on DermaSilk silk knitwear performs a biocide action against the fungus Malassezia Furfur. (Test carried out by Prof. P. Mandrioli of the CNR – Istituto ISAC – Bologna).
- Microbiological Test: Certifies that the polymerised antimicrobial on DermaSilk silk knitwear prevents the growth of the bacterium Staphylococcus aureus without releasing substances into the environment (Test carried out at the Experimental Station of the Milan Polytechnic).
- Test in vitro. Demonstrates that DermaSilk does not act by release and therefore does not alter the natural microbial equilibrium of the organism (Vittorio Sambri et al., Department of Haematology, Oncology and Microbiology - Bologna University

Download the Bibliography about DermaSilk